Coffee Addiction All in the Genes

Coffee Addiction All in the Genes

Everyone reacts differently to coffee, whether you can’t enough of it or if one cup of Joe has you wired for the rest of the day.  Researchers have gained some insight into how caffeine affects the body, and the answer could be in your genes.

Genetic variants associated with habitual coffee drinking and how the body reacts to caffeine have been pinpointed by scientists, according to a new study published in the journal Molecular Psychiatry.

Six new genetic variants were pinpointed, four of which involve genes associated with caffeine including how it is broken down by the body as well as its stimulating effects.  The two other genes, while not clearly linked to caffeine, are linked with cholesterol levels and blood sugar.

Researchers analyzed 20,000 regular coffee drinkers and the results of previous studies where participants stated the amount of coffee they consumed in a day.  The participants also had their DNA scanned. The researchers then looked for differences in the DNA of participants who consumed various levels of coffee.

These new findings could provide useful insight into how and why different amounts of coffee has different effects on different people.

The U.S. is the world’s largest consumer of coffee, with over 80 percent of the adult population being coffee drinkers, an average of three cups a day per person, according to the National Coffee Association.


Sources: Molecular Psychiatry
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